PAPP‐A: a promising therapeutic target for healthy longevity
Pregnancy‐associated plasma protein‐A (PAPP‐A) is a proteolytic enzyme that was discovered to increase local insulin‐like growth factor (IGF) availability for receptor activation through cleavage of …
The Pregnancy-Associated Plasma Protein-A (PAPP-A) Story
Jun 2, 2023 · Pregnancy-associated plasma protein-A (PAPP-A) was first identified in the early 1970s as a placental protein of unknown function, present at high concentrations in the circulation of pregnant …
Structural insights into the covalent regulation of PAPP-A ... - Nature
Dec 22, 2022 · Originally discovered in the circulation of pregnant women as a protein secreted by placental trophoblasts, the metalloprotease pregnancy-associated plasma protein A (PAPP-A) is also …
PAPP-A (Pregnancy Associated Plasma Protein A) Test
Nov 29, 2023 · Pregnancy-associated plasma Protein A, commonly known as PAPPA, is a protein produced by the placenta during pregnancy. It is a crucial biomarker used to assess foetal well-being …
PAPP-A Levels in Pregnancy: Interpreting Your Results
Jul 23, 2025 · Understand your PAPP-A results from first-trimester screening. Learn how this biomarker offers insight into fetal development and placental health.
PAPP-A Test: Everything You Need to Know - pregnancyarchive.com
The PAPP-A test, also known as Pregnancy-Associated Plasma Protein-A test, is a blood test conducted during early pregnancy to assess the levels of a specific protein called PAPP-A. PAPP-A …
Understanding Normal Papp-A Levels In Pregnancy: What You
Dec 29, 2023 · PAPP-A stands for pregnancy-associated plasma protein-A and it is produced by the placenta during pregnancy. While PAPP-A levels can vary from woman to woman, there is a range …
PAPP-A Values: Significance and Importance in Pregnancy
Among various routine tests, the PAPP-A values (Pregnancy-Associated Plasma Protein A) test plays a crucial role. In this article, we will explore in detail what PAPP-A is, how it’s measured, what are …
How the PAPP-A Test Checks Your Baby’s Growth in Early Pregnancy
Aug 27, 2025 · The PAPP-A blood test in early pregnancy helps screen for potential growth issues and complications. Learn what it means, when it’s done, and why it matters.
Variation of Papp-A Level in the First Trimester of Pregnancy and Its ...
PAPP-A is a large glycoprotein produced by the placenta and decidua thought to have several functions, including prevention of recognition of the fetus by the maternal immune system, matrix …