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  1. Sickle Cell Disease - Causes and Risk Factors | NHLBI, NIH

    Aug 20, 2024 · Sickle cell disease is sometimes called sickle cell anemia. People have sickle cell trait if they inherit a copy of the sickle cell gene from one parent and a copy of the gene for normal …

  2. Sickle Cell Disease - What Is Sickle Cell Disease? - NHLBI, NIH

    Dec 10, 2025 · Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells. Normally, red blood …

  3. Sickle Cell Disease - Symptoms | NHLBI, NIH

    Aug 20, 2024 · Sickle cell disease is an inherited disease, which means you are born with it. However, most babies do not have problems from the disease before they are about 5 or 6 months old. …

  4. Sickle Cell Genetics and Pathophysiology - NHLBI, NIH

    Sickle Cell Genetics and Pathophysiology Research in the Laboratory of Sickle Cell Genetics and Pathophysiology, led by Dr. Swee Lay Thein, examines the genetic and biological factors underlying …

  5. Sickle Cell Disease Research - NHLBI, NIH

    Aug 23, 2024 · The National Institutes of Health (NIH) has supported research on sickle cell disease — also called sickle cell anemia — since before the NHLBI’s founding in 1948. With each passing …

  6. Living With Sickle Cell Disease - NHLBI, NIH

    Aug 22, 2024 · Living with sickle cell disease involves receiving routine follow-up care, learning to manage a pain crisis, adopting a healthy lifestyle, and preventing health problems for yourself or your …

  7. Sickle Cell Branch - NHLBI, NIH

    Research in the Laboratory of Sickle Cell Genetics and Pathophysiology, led by Dr. Swee Lay Thein, examines the genetic factors underlying the phenotypic variability of sickle cell disease and beta …

  8. Sickle Cell Disease Fact Sheet - NHLBI, NIH

    Sickle cell disease (SCD) is the most common inherited blood disorder in the United States. In this fact sheet, learn about the causes, signs and symptoms, diagnosis, and treatment of SCD.

  9. Sickle Cell Disease - Treatment | NHLBI, NIH

    Sep 30, 2024 · Treatment options for sickle cell disease include medicines that lessen symptoms, blood transfusions, blood and bone marrow transplants, and gene therapy treatments. Bone marrow …

  10. The National Sickle Cell Anemia Control Act provides for the establishment of voluntary sickle cell disease screening, patient counseling, public and professional education, and research and training …