🩸 Antimetabolites = block DNA synthesis. No purines. No pyrimidines. No DNA → no cell division. Think: MTX → ↓ DHFR 5-FU → ↓ thymidylate synthase 6-MP → ↓ purine synthesis High-yield hematology made simple for Step 1. This is how we connect pathways inside our USMLE Step 1 All-in-One Course. 🔥 #USMLEStep1 #Hematology #Antimetabolites #pharmacology #usmle | Dr. Heba Tutoring
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🧬 DNA Base Pairing – The Language of Life! 🔬 DNA carries our genetic information, and its structure is based on a very specific rule called base pairing. The DNA molecule has four nitrogenous bases, divided into two groups: 🟣 Pyrimidines: Thymine (T) Cytosine (C) 🔵 Purines: Adenine (A) Guanine (G) Base pairing follows a strict principle known as Chargaff’s Rule. According to this rule: ✨ Adenine (A) always pairs with Thymine (T) through 2 hydrogen bonds ✨ Guanine (G) always pairs with Cytosi
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