Recent research continues to show that there is no health benefit to drinking alcohol, even at low or “moderate” levels. As a result, more people are rethinking their relationship with alcohol, and I’m all for it. The challenge is often figuring out what to reach for instead, especially in social settings. I’ve been testing a number of non-alcoholic options and have found a few that check important boxes. One of the most overlooked factors is sugar content. Sugar is something many people do not
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Recent research continues to show that there is no health benefit to drinking alcohol, even at low or “moderate” levels. As a result, more people are rethinking their relationship with alcohol, and I’m all for it. The challenge is often figuring out what to reach for instead, especially in social settings. I’ve been testing a number of non-alcoholic options and have found a few that check important boxes. One of the most overlooked factors is sugar content. Sugar is something many people do not
4.8K views2 months ago
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Alzheimer’s: 12 Vitamins, Foods, Exercises for Brain Metabolism | David Perlmutter, MD
Alzheimer’s: 12 Vitamins, Foods, Exercises for Brain Metabolism | David Perlmutter, MD
8.2K views1 month ago
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Our friend Dr David Perlmutter reccomends allulose! #Allulose #RxSugar #realsugar #Keto #GlutenFree #vegan #Vegetarian #baking #Paleo #davidperlmutter
Our friend Dr David Perlmutter reccomends allulose! #Allulose #RxSugar #realsugar #Keto #GlutenFree #vegan #Vegetarian #baking #Paleo #davidperlmutter
14.5K viewsSep 6, 2023
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David Perlmutter, M.D. explains why humans adapted to loving sugar. | Lewis Howes
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David Perlmutter, M.D. explains why humans adapted to loving sugar. | Lewis Howes
35.3K viewsOct 20, 2023
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Dr. David Perlmutter explains why fructose is the most toxic sugar for your brain and Alzheimer’s risk. | Lewis Howes
4:04
Dr. David Perlmutter explains why fructose is the most toxic sugar for your brain and Alzheimer’s risk. | Lewis Howes
25.3K views7 months ago
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Is allulose just a sugar replacement or are there actual health benefits? Let’s dive in… | David Perlmutter, M.D.
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Is allulose just a sugar replacement or are there actual health benefits? Let’s dive in… | David Perlmutter, M.D.
4.4K viewsMar 27, 2024
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How does your blood sugar impact your brain? The connection might surprise you—and it’s more important than ever to understand. You can download my free Diabetes Guide for prevention, management and reversal here: https://drperlmutter.com/guides/focus-on-diabetes/ | David Perlmutter, M.D.
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How does your blood sugar impact your brain? The connection might surprise you—and it’s more important than ever to understand. You can download my free Diabetes Guide for prevention, management and reversal here: https://drperlmutter.com/guides/focus-on-diabetes/ | David Perlmutter, M.D.
2.3K viewsJan 20, 2025
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Do you regularly opt for erythritol as a blood-sugar friendly sweetener? You may need to reconsider. New research suggests consumption of erythritol could mean higher oxidative stress and reduced nitric oxide, both of which impair cardiovascular and metabolic health. Findings even connect high circulating erythritol with increased clot risk. Safer alternatives such as monk fruit and allulose (my personal favorite) don’t appear to share these downsides and may offer additional metabolic benefits.
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Do you regularly opt for erythritol as a blood-sugar friendly sweetener? You may need to reconsider. New research suggests consumption of erythritol could mean higher oxidative stress and reduced nitric oxide, both of which impair cardiovascular and metabolic health. Findings even connect high circulating erythritol with increased clot risk. Safer alternatives such as monk fruit and allulose (my personal favorite) don’t appear to share these downsides and may offer additional metabolic benefits.
3.1K views9 months ago
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If you are working to cut back on sugar, a sweetener I often recommend is allulose. It’s a naturally occurring sugar that does not raise blood sugar or interfere with insulin function. It also avoids the cardiovascular concerns that have been linked to some sugar alcohols such as erythritol. If you want something sweet, give allulose a try. It can be a smarter choice that supports both metabolic and brain health. | David Perlmutter, M.D.
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If you are working to cut back on sugar, a sweetener I often recommend is allulose. It’s a naturally occurring sugar that does not raise blood sugar or interfere with insulin function. It also avoids the cardiovascular concerns that have been linked to some sugar alcohols such as erythritol. If you want something sweet, give allulose a try. It can be a smarter choice that supports both metabolic and brain health. | David Perlmutter, M.D.
6.3K views4 months ago
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Is allulose a GLP-1 agonist? Can it be used as a sugar substitute? I’m answering both of these questions for you today. Wishing everyone a Happy Labor Day! | David Perlmutter, M.D.
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Is allulose a GLP-1 agonist? Can it be used as a sugar substitute? I’m answering both of these questions for you today. Wishing everyone a Happy Labor Day! | David Perlmutter, M.D.
3.6K viewsSep 4, 2023
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Berberine has become a popular supplement for supporting healthy blood sugar. I was recently asked whether it should be taken before high-carb meals. Here's my perspective: Berberine activates the same metabolic pathway as metformin, called AMPK. While that’s promising, the most effective and reliable way to activate this pathway is through regular movement and exercise. Berberine can be a helpful tool, yet it works best as part of a thoughtful daily routine (supplementing and movement), not as
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Berberine has become a popular supplement for supporting healthy blood sugar. I was recently asked whether it should be taken before high-carb meals. Here's my perspective: Berberine activates the same metabolic pathway as metformin, called AMPK. While that’s promising, the most effective and reliable way to activate this pathway is through regular movement and exercise. Berberine can be a helpful tool, yet it works best as part of a thoughtful daily routine (supplementing and movement), not as
7.2K views8 months ago
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How do we know if a food is inflammatory? Today’s discussion is around blood sugar and how to keep it in control. Let’s dig into it… | David Perlmutter, M.D.
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How do we know if a food is inflammatory? Today’s discussion is around blood sugar and how to keep it in control. Let’s dig into it… | David Perlmutter, M.D.
17.8K viewsDec 10, 2022
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Here’s what you’ll learn in my free diabetes guide: ➡️ The truth behind “sugar-free” ➡️ How blood sugar affects Alzheimer’s risk and your microbiome ➡️ The new evidence that dispels popular misconceptions about diabetes ➡️ An actionable plan for diabetes prevention, management and reversal Download it here: https://drperlmutter.com/guides/focus-on-diabetes/ | David Perlmutter, M.D.
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Here’s what you’ll learn in my free diabetes guide: ➡️ The truth behind “sugar-free” ➡️ How blood sugar affects Alzheimer’s risk and your microbiome ➡️ The new evidence that dispels popular misconceptions about diabetes ➡️ An actionable plan for diabetes prevention, management and reversal Download it here: https://drperlmutter.com/guides/focus-on-diabetes/ | David Perlmutter, M.D.
1.2K viewsNov 19, 2024
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Today on The Empowering Neurologist, I’m joined by Dr. Melissa Schilling, of New York University, to discuss the empowering topic of Alzheimer’s prevention. As you’re all well aware, this is a subject at the core of my work, and Dr. Schilling’s recent findings, on the role of blood sugar in brain health, could be a game changer. Hope you enjoy. http://www.drperlmutter.com/empowering-neurologist-david-perlmutter-md-dr-melissa-schilling/ | David Perlmutter, M.D.
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Today on The Empowering Neurologist, I’m joined by Dr. Melissa Schilling, of New York University, to discuss the empowering topic of Alzheimer’s prevention. As you’re all well aware, this is a subject at the core of my work, and Dr. Schilling’s recent findings, on the role of blood sugar in brain health, could be a game changer. Hope you enjoy. http://www.drperlmutter.com/empowering-neurologist-david-perlmutter-md-dr-melissa-schilling/ | David Perlmutter, M.D.
23.6K viewsJun 8, 2016
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This is a message of hope, and I want to be sure it comes through clearly: Parkinson’s isn’t just about genetics. While we can’t change our DNA, we can influence many of the other factors that affect risk, such as blood sugar imbalance, toxin exposure, and repeated head trauma. Type 2 diabetes, for example, is linked to a significantly higher risk of Parkinson’s. But because it’s often preventable through nutrition and lifestyle, that gives us more control than we may realize. From your plate to
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This is a message of hope, and I want to be sure it comes through clearly: Parkinson’s isn’t just about genetics. While we can’t change our DNA, we can influence many of the other factors that affect risk, such as blood sugar imbalance, toxin exposure, and repeated head trauma. Type 2 diabetes, for example, is linked to a significantly higher risk of Parkinson’s. But because it’s often preventable through nutrition and lifestyle, that gives us more control than we may realize. From your plate to
3.5K views9 months ago
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By 2060, dementia cases are expected to double. While aging may play a role, lifestyle factors are just as critical—and that means there are things you can do today to protect your brain. ✅ Prioritize metabolic health: High blood sugar and insulin resistance increase your risk. Monitoring fasting insulin and wearing a continuous glucose monitor can help you stay on track. ✅ Move your body: Exercise is one of the most powerful ways to protect your brain and reduce risk. With no meaningful pharmac
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By 2060, dementia cases are expected to double. While aging may play a role, lifestyle factors are just as critical—and that means there are things you can do today to protect your brain. ✅ Prioritize metabolic health: High blood sugar and insulin resistance increase your risk. Monitoring fasting insulin and wearing a continuous glucose monitor can help you stay on track. ✅ Move your body: Exercise is one of the most powerful ways to protect your brain and reduce risk. With no meaningful pharmac
11.8K viewsApr 1, 2025
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In this guide, you will learn: 😱 The truth behind “sugar-free” 🫀 How blood sugar affects Alzheimer’s risk and your microbiome 📄 The new evidence that dispels popular misconceptions about diabetes 💯 An actionable plan for diabetes prevention and management Click the "Sign up" button below and get your diabetes guide! | David Perlmutter, M.D.
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In this guide, you will learn: 😱 The truth behind “sugar-free” 🫀 How blood sugar affects Alzheimer’s risk and your microbiome 📄 The new evidence that dispels popular misconceptions about diabetes 💯 An actionable plan for diabetes prevention and management Click the "Sign up" button below and get your diabetes guide! | David Perlmutter, M.D.
88.3K views1 year ago
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As a neurologist, I welcome any advancement in early Alzheimer's detection and research. That said, I always come back to this: even though we don’t have all the answers yet, we do know a lot about how to support long-term brain health. We can choose daily habits that reduce our risk, such as regular exercise, restorative sleep, blood sugar balance, meaningful connection, and targeted nutrition. In my opinion, there’s no need to wait for a diagnosis to take action. | David Perlmutter, M.D.
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As a neurologist, I welcome any advancement in early Alzheimer's detection and research. That said, I always come back to this: even though we don’t have all the answers yet, we do know a lot about how to support long-term brain health. We can choose daily habits that reduce our risk, such as regular exercise, restorative sleep, blood sugar balance, meaningful connection, and targeted nutrition. In my opinion, there’s no need to wait for a diagnosis to take action. | David Perlmutter, M.D.
17.6K views10 months ago
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Let’s talk about sprouts and their incredible benefits ranging from immune system support to blood sugar regulation. Want to test out growing your own broccoli sprouts? Here are my simple steps: https://drperlmutter.com/simple-steps-for-growing-broccoli-sprouts/ | David Perlmutter, M.D.
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Let’s talk about sprouts and their incredible benefits ranging from immune system support to blood sugar regulation. Want to test out growing your own broccoli sprouts? Here are my simple steps: https://drperlmutter.com/simple-steps-for-growing-broccoli-sprouts/ | David Perlmutter, M.D.
1.6K viewsJul 9, 2024
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If fasting insulin levels are high, that means you may be on your way toward insulin resistance — the harbinger for type 2 diabetes. If you’re interested in taking control of your health destiny, I would encourage you to make sure your practitioner is not only testing your blood sugar level, but your fasting insulin level as well. | David Perlmutter, M.D.
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If fasting insulin levels are high, that means you may be on your way toward insulin resistance — the harbinger for type 2 diabetes. If you’re interested in taking control of your health destiny, I would encourage you to make sure your practitioner is not only testing your blood sugar level, but your fasting insulin level as well. | David Perlmutter, M.D.
2.2K viewsDec 27, 2023
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Fructose is not the only thing that raises uric acid. Here’s one you may not have guessed… | David Perlmutter, M.D.
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Fructose is not the only thing that raises uric acid. Here’s one you may not have guessed… | David Perlmutter, M.D.
21.1K viewsMar 14, 2023
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When it comes to bloodwork, we want to be in the optimal range, not just the normal range. To achieve that means checking your blood sugar more than once a year during your annual doctor’s visit. I discuss why I think blood sugar control is one of the most important things for global health with @CaseyMeansMD on the Empowering Neurologist. Listen to the full episode here: https://youtu.be/8fpBY95qEiw?si=_kZ5midp2pa56SLj | David Perlmutter, M.D.
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When it comes to bloodwork, we want to be in the optimal range, not just the normal range. To achieve that means checking your blood sugar more than once a year during your annual doctor’s visit. I discuss why I think blood sugar control is one of the most important things for global health with @CaseyMeansMD on the Empowering Neurologist. Listen to the full episode here: https://youtu.be/8fpBY95qEiw?si=_kZ5midp2pa56SLj | David Perlmutter, M.D.
4.2K viewsJun 13, 2024
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You asked, I’m here to answer. Today I’m sharing my thoughts on artificial sweeteners — whether or not they should be avoided, their effect on the microbiome and insights from a new study that looks at their risk on cardiovascular diseases. | David Perlmutter, M.D.
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You asked, I’m here to answer. Today I’m sharing my thoughts on artificial sweeteners — whether or not they should be avoided, their effect on the microbiome and insights from a new study that looks at their risk on cardiovascular diseases. | David Perlmutter, M.D.
7.2K viewsNov 28, 2022
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Could your favorite snack be hiding mold? Let’s talk about: 🥜 Why buying bulk nuts might not be the best choice 🥜 The best ways to store nuts to reduce mold risk 🥜 Should you roast or eat them raw? Got a health question? Drop it here and I may answer it in a future video. | David Perlmutter, M.D.
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Could your favorite snack be hiding mold? Let’s talk about: 🥜 Why buying bulk nuts might not be the best choice 🥜 The best ways to store nuts to reduce mold risk 🥜 Should you roast or eat them raw? Got a health question? Drop it here and I may answer it in a future video. | David Perlmutter, M.D.
5.5K viewsFeb 13, 2025
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Could GLP-1 drugs such as Ozempic reduce the risk of Alzheimer’s disease? Research continues to point to the importance of blood sugar control and metabolic health for brain health. When blood sugar levels frequently spike and crash, it creates inflammation and oxidative stress—two factors that can damage brain cells and impair memory. Over time, these blood sugar fluctuations create insulin resistance, which has been found to be a key player in Alzheimer’s and other cognitive decline. Keeping b
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Could GLP-1 drugs such as Ozempic reduce the risk of Alzheimer’s disease? Research continues to point to the importance of blood sugar control and metabolic health for brain health. When blood sugar levels frequently spike and crash, it creates inflammation and oxidative stress—two factors that can damage brain cells and impair memory. Over time, these blood sugar fluctuations create insulin resistance, which has been found to be a key player in Alzheimer’s and other cognitive decline. Keeping b
1.3K viewsNov 16, 2024
FacebookDavid Perlmutter, M.D.
Most people wouldn’t start their day with a can of soda, but many don’t think twice about a glass of orange juice. The sugar content is nearly identical. I recently spoke to PARADE Magazine about this very issue, highlighting how common “health” foods like orange juice and granola bars can actually spike blood sugar and harm brain health over time: https://parade.com/health/these-snacks-can-increase-dementia-risk-according-to-neuroscientists Understanding how sugar impacts your metabolic health
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Most people wouldn’t start their day with a can of soda, but many don’t think twice about a glass of orange juice. The sugar content is nearly identical. I recently spoke to PARADE Magazine about this very issue, highlighting how common “health” foods like orange juice and granola bars can actually spike blood sugar and harm brain health over time: https://parade.com/health/these-snacks-can-increase-dementia-risk-according-to-neuroscientists Understanding how sugar impacts your metabolic health
6.9K views8 months ago
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Food marketing has become very good at borrowing the language of health. Words like “natural,” “plant-based,” and “from coconuts” are often used to create a sense of safety around ingredients that still behave the same way in the body. Sugar is one of the clearest examples of this disconnect. From a metabolic perspective, the source matters far less than the physiological response. Added sugars, regardless of origin, place a burden on blood sugar regulation and insulin signaling. Over time, that
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Food marketing has become very good at borrowing the language of health. Words like “natural,” “plant-based,” and “from coconuts” are often used to create a sense of safety around ingredients that still behave the same way in the body. Sugar is one of the clearest examples of this disconnect. From a metabolic perspective, the source matters far less than the physiological response. Added sugars, regardless of origin, place a burden on blood sugar regulation and insulin signaling. Over time, that
2.8K views2 months ago
FacebookDavid Perlmutter, M.D.
I recently shared about berberine, a natural compound that supports fat metabolism and improves insulin sensitivity in a way similar to metformin. Since then, I’ve been asked whether eating barberries can provide a natural source of berberine. Barberries do contain berberine, usually around 5–7 percent, but the amount varies and you would need to eat a lot to reach an effective dosage. That’s why a high-quality berberine supplement is usually more reliable. Barberries and other nutrient-dense fr
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I recently shared about berberine, a natural compound that supports fat metabolism and improves insulin sensitivity in a way similar to metformin. Since then, I’ve been asked whether eating barberries can provide a natural source of berberine. Barberries do contain berberine, usually around 5–7 percent, but the amount varies and you would need to eat a lot to reach an effective dosage. That’s why a high-quality berberine supplement is usually more reliable. Barberries and other nutrient-dense fr
3K views7 months ago
FacebookDavid Perlmutter, M.D.
Not all sweeteners are created equal, but one in particular is showing some powerful promise. In this clip from my conversation with Dr. @dominic.dagostino.kt on The Empowering Neurologist, we break down why allulose may be one of the most metabolically friendly sugar alternatives out there. It’s: ✔️ Naturally occurring ✔️ Low in calories ✔️ Shown to have minimal impact on insulin and blood sugar ✔️ Potentially supportive of gut and GLP-1 function Dr. D’Agostino shares how he’s seen blood glucos
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Not all sweeteners are created equal, but one in particular is showing some powerful promise. In this clip from my conversation with Dr. @dominic.dagostino.kt on The Empowering Neurologist, we break down why allulose may be one of the most metabolically friendly sugar alternatives out there. It’s: ✔️ Naturally occurring ✔️ Low in calories ✔️ Shown to have minimal impact on insulin and blood sugar ✔️ Potentially supportive of gut and GLP-1 function Dr. D’Agostino shares how he’s seen blood glucos
5.3K views10 months ago
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Can a keto diet support mental health? I spoke with @georgiaedemd who co-authored the first inpatient study of the ketogenic diet for serious mental illness, developed the first medically accredited course in ketogenic diets for mental health, and is a recipient of the Baszucki Brain Research Fund's Metabolic Mind Award. During our conversation we discuss: ✅ The profound connection between food and mental health ✅ Why robust mental health begins with metabolic health ✅ Practical, science-backed
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Can a keto diet support mental health? I spoke with @georgiaedemd who co-authored the first inpatient study of the ketogenic diet for serious mental illness, developed the first medically accredited course in ketogenic diets for mental health, and is a recipient of the Baszucki Brain Research Fund's Metabolic Mind Award. During our conversation we discuss: ✅ The profound connection between food and mental health ✅ Why robust mental health begins with metabolic health ✅ Practical, science-backed
10.8K viewsJan 16, 2025
FacebookDavid Perlmutter, M.D.
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